ELISA SUBSTRATE BUFFER  (E.S.B.)

Contact: Ometa Herman

 

0.05M Sodium Phosphate

0.02M Citric Acid

 

MAKE UP

 

0.2M    Sodium Phosphate

            Na2HPO4                                                       FW142.00

            28.4g/liter 

 

            (0.2M = 4X)   

            (0.2M divided 0.05M=4(X))                                                   

            (1000ml (1L) divided 4 = 250mls)                    250mls

 

0.1M    Citric Acid

            (HOC(COOH)(CH2COOH)2.H2O                FW210.1

            21.01g/liter

 

            (0.1M = 5X)

            (0.1M divided 0.02M = 5(X))                                     

            (1000ml (1L) divided 5 = 200mls)                    200mls

 

 

distilled H2O                                                                            550mls

 

                                                                        final total        1000mls (1L)

 

 

Add 500ml d H2O only

 

Check pH   ( pH should be ph5.0 to 5.13) bring the soln to correct pH use only

 

0.2M   Sodium Phosphate                  (BASE) brings it up

0.1M   Citric Acid                              (ACID) brings it down

 

 

ON ALL BUFFERS MADED THE LABEL MUST HAVE

DATE/CLASSIFICATION LETTER/ INITIALS