Wayne Moore has led software development effort in the Herzenberg Laboratory for the past twenty years. Moore designed and implemented the initial (PDP-11) system used to collect and analyze FACS data (ca.1980) as well as subsequent programs ("FACS/Desk") on the DEC-VAX 780. In 1983, he developed FACS/Desk, a comprehensive data acquisition, management and analysis system. Since that time, FACS/Desk has been running continuously, with periodic updates at Stanford and other locations worldwide. It has served hundreds of biologists and provides access to several hundred gigabytes of FACS data, which is currently stored online or in its online-accessible tape archive.

Moore is currently designing and building an innovative internet-based system that will replace FACS/Desk with state of the art communications software and methods for cataloging and retrieving data according to annotations that define the context in which the data was collected. He is also a highly competent mathematician and statistician and will introduce new methods for visualizing interpreting FACS data in the new system.

Publications:

Herzenberg, L.A., W. Moore, D. Parks. 1998. Data Annotation: The Heart of the Laboratory Notebook. . W.f. Word, editor.

Bigos, M., Parks, David R., Moore, Wayne A., Herzenberg, L.A., Herzenberg, L.A. 1994. Pattern sorting: A computer controlled multidimensional sorting method using K-D trees. Cytometry. 16:357-363.

Staal, F.J.T., M. Roederer, D.M. Israelski, J. Bubp, L.A. Mole, D. McShane, S.C. Deresinski, W. Ross, H. Sussman, P.A. Raju, M.T. Anderson, W. Moore, S.W. Ela, L.A. Herzenberg, and L.A. Herzenberg. 1992. Intracellular glutathione levels in T cell subsets decrease in HIV infected individuals. AIDS Res. Human Retrov. 8:305-314.

Staal, F.J.T., M. Roederer, J. Bubp, L.A. Mole, M.T. Anderson, P.A. Raju, D.M. Israelski, S.C. Deresinski, W.A. Moore, L.A. Herzenberg, and L.A. Herzenberg. 1992. CD20 expression is increased on B lymphocytes from HIV-infected individuals. J. Acq. Immun. Defic. Syndrome. 5:627-632 (and erratum sheet, p. 954).

Moore, W., and R. Kautz. 1986. Data analysis for flow cytometry. In The Handbook of Experimental Immunology. Vol. 1; Immunochemistry. L.A.H. D.M. Weir, C.C. Blackwell, and L.A. Herzenberg, editor. Blackwell Scientific Publications, Ltd., Edinburgh. 30.1 -.

Herzenberg, L.A., A.M. Stall, P.A. Lalor, W.A. Sidman, W.A. Moore, D.R. Parks, and L.A. Herzenberg. 1986. The Ly-1 B cell lineage. Immunol. Rev. 93:81-102.